RAF Typhoon jets have conducted a mission with France's air force in a coordinated attack on an hidden munitions depot in Syria operated by the IS group, according to the UK's MoD.
The location, identified by intelligence, was assessed as housing weapons and explosive materials, the statement said, and was situated in mountainous terrain just above the historic site of Palmyra in central Syria.
"The RAF jets utilized laser-guided Paveway IV weapons to strike a number of approach shafts providing entry to the site... early reports suggest the objective was successfully hit," officials stated.
There was no indication of any harm to civilians in the operation on Saturday evening and each participating jet returned to base without incident, the ministry further stated.
The Typhoon FGR4s were assisted by a Voyager aerial refuelling aircraft.
The Islamic State group - alternatively referred to as Daesh - imposed extremist governance over large swathes of both Syria and Iraq prior to its 2019 collapse.
"This action underscores British leadership, and determination to operate in unison with our partners, to eliminate any revival of the terrorist group and their dangerous and violent ideologies in the area," Britain's Defence Chief the Defence Secretary stated.
UK warplanes have conducted surveillance missions over Syrian airspace to "prevent any efforts to regroup" of IS after its defeat at the battle of Baghuz in 2019, the authorities noted.
"I must thank all the members of British forces involved in this mission for their skill and their courage," he commented. "Including them were a great many British troops on duty over Christmas and New Year. This action, to remove terrorist threats who pose a risk to our way of life, shows how our armed forces are ready to step up, all year round, ensuring Britain's security domestically and powerful internationally."
In December, the US military executed what it described as a "massive strike" against Daesh sites in Syria, subsequent to an assault killed two US servicemembers and a civilian interpreter in Palmyra.
The United Nations says IS still maintains an estimated 5,000 to 7,000 militants in Iraq and Syria.